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The profound connection between physical fitness and cognitive well-being has become an area of immense scientific interest. Strength training, long regarded as essential for muscle development and overall physical health, is now recognized for its significant impact on brain function and mental performance. Emerging research demonstrates that resistance training not only enhances memory and cognitive abilities but also contributes to the prevention of neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. Furthermore, as scientific advancements continue to push the boundaries of medicine, gene therapy is emerging as a potential tool for neural enhancement. Understanding how strength training influences brain health and how gene therapy may complement these benefits provides a fascinating glimpse into the future of cognitive enhancement and disease prevention.